Patrick Patterson opened the scoring on UK's first possession with a straight-away three-pointer with 18:44 on the clock. It extended UK's streak of 742 consecutive games with a three-point basket.
Kentucky jumped out to a 5-0 lead and never trailed.
Harris, Krebs and Stevenson played the first 5:23 of the game before being replaced at the 14:37 mark. UK had a 7-3 lead at that point.
Ahead 20-16, UK went on a 14-0 run for a 34-16 lead with 5:20 to go, the Wildcats' largest advantage of the half.
Florida went on a hot streak in the final five minutes of the half, cutting the lead to 41-31 by intermission.
Kentucky made 6-of-12 three-point shots in the first half. It is the second-consecutive game that the Wildcats made six threes in the first half.
Florida gradually chipped away in the second half and pulled within two, 60-58, at the 6:52 mark. The Gators got the ball back but had a turnover and Patrick Patterson hit a short jumper.
Florida again pulled within two, 62-60, with 5:28 to go, but the Wildcats got the next six points on a three-pointer by Wall, a foul shot by Wall and two foul shots by Darnell Dodson for a 68-60 cushion.
After Florida had pulled within 59-56 with 10:52 to play, the Gators scored only 10 more points the remainder of the game.
Kentucky had five players score in double figures, the first time that happened since the Vanderbilt game on Jan. 30.